Wordose Answer — April 28, 2026

Toxicity occurs when drug levels exceed the therapeutic range, causing harmful effects that can range from mild symptoms to organ failure and death. Nurses must monitor therapeutic drug levels for medications with narrow therapeutic indices such as digoxin, lithium, vancomycin, and aminoglycosides, and recognize early signs of toxicity specific to each drug. Prompt identification and reporting of toxic symptoms, holding the offending medication, and supporting the patient with appropriate antidotes and supportive care are critical nursing interventions that prevent serious adverse outcomes.

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